> ## Content Index
> Fetch the complete content index at: https://bioinformatics.ghost.io/llms.txt
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# Difference between Input and IgG
- URL: https://bioinformatics.ghost.io/difference-between-input-and-igg/
- Published: 2018-05-30T01:05:27.000Z
- Updated: 2018-05-30T01:05:27.000Z
- Author: Aarthi Ramakrishnan
- Tags: programming, #Import 2026-08-27 15:34

Although a little outdated, this article explains the difference between using Input and IgG as a control for ChIP-seq analysis well:

[Getting started with ChIP seq](https://epigenie.com/guide-getting-started-with-chip-seq/?ref=bioinformatics.ghost.io)

The following biostars links are useful too:

- [Input, Igg Or Untagged Strain](https://www.biostars.org/p/15817/?ref=bioinformatics.ghost.io)
- [Which ChIP-seq IgG to use](https://www.biostars.org/p/215222/?ref=bioinformatics.ghost.io)
- [control used (IgG/Input)](https://www.biostars.org/p/300621/?ref=bioinformatics.ghost.io)

Input samples are generally preferred over IgG, as they work best while using MACS for peak calling.